When "Supernatural" returns next year, it will pay homage to Angelina Jolie-starring movie "Girl, Interrupted". The episode which is called "Sam, Interrupted" will see Sam being strapped to a bed inside what could be said a psych ward. From the casting sides, it is said that strange happenings are afoot in the place. "Sam, Interrupted" is airing on January 14. The show takes a two-month break and will return with the second half of the season including the 100th episode. EW said that the monumental episode will be particularly huge for Jensen Ackles aka Dean.
Some spoilers about the future episodes airing in 2010 have been revealed including one where Sam and Dean switch bodies in episode "Being Sam Winchester". There is also an episode where Anna returns and wants to kill Sam. She plans to exterminate Mary and John Winchester who will be seen in their younger years.